AYANI is a nested cohort within global IeDEA that recruits and follows adolescents and young adults living with HIV (ALWH), conducting ongoing, in-depth data collection around the specific biological, mental, social, and cultural factors that may impact their health outcomes. Addressing site-level determinants of outcomes, individual-level determinants, and route of HIV transmission, and using the rich prospective data collected from this cohort, AYANI aims to:
- Describe care engagement patterns (retention, losses-to-follow up), transition indicators (self-care, socio-demographic data), viral suppression, and mortality among adolescents and young adults living with HIV.
- Examine the correlates of key clinical and socio-demographic factors with retention and viral non-suppression among adolescents and young adults living with HIV.
In Central Africa IeDEA, there are two AYANI sites in Rwanda, which have enrolled 125 ALWH aged 15-24 years for AYANI baseline and follow-up assessments, including almost 80% with perinatally-acquired HIV.